TAK 242 inhibited a series of LPS-induced biological pathways: pathways in cancer (mmu05200; gene count: 47), human papillomavirus infection (mmu05165; gene count: 31), microRNAs in cancer (mmu05206; gene count: 21), focal adhesion (mmu04510; gene count: 21), and TNF signaling pathway (mmu04668; gene count: 20) (Supplementary Table S14) (Figure 4E,G). The gene discussed is TNF; the disease is cancer.