TNF and congenital rubella syndrome: For example, cytokines involved in CAR-T therapy-triggered CRS include IFN-γ, IL-2, IL-2Rα, IL-6, sIL-6R, granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-1, IL-10, IL-12, tumor necrosis factor-α (TNF-α), IFN-α, MCP-1, and macrophage inflammatory protein-1α (MIP-1α) [8,24,25].