As another example, monitoring of COVID-19-associated CRS patient cytokine profiles in 2019 revealed higher levels of IL-2, IL-7, IL-10, G-SCF, MCP-1, MIP-1α, and TNF-α in plasma of intensive care unit (ICU) patients versus plasma of non-ICU patients [16]. The gene discussed is IL10; the disease is congenital rubella syndrome.