In contrast with results in some other cancers [143] and regulation by estrogen of some chemokine receptors [144,145,146] interacting with ERα in positive feedback, and despite the expected sex biased regulation of inflammation and chemokines [147,148,149], there is no indication of sex difference in the chemokine or chemokine receptor profile in thyroid cancer [150,151,152,153,154,155,156]. This evidence concerns the gene ESR1 and thyroid gland carcinoma.