In addition, hypomethylation and an increase in expression after endurance exercise were observed in the genes of the transcription factors MEF2A and Runt-Related Transcription Factor 1 (RUNX1), T2D-related THADA, NADH respiratory chain: Ubiquinone Oxidoreductase Subunit C2 (NDUFC2), and also Interleukin 7 (IL-7). The gene discussed is THADA; the disease is type 2 diabetes mellitus.