IL10 and allergic disease: Support for a role of Tregs in the allergy protective effects of M. vaccae NCTC 11659 comes from Hunt and colleagues [75], who first showed higher IL-10, but not IFNγ and IL-12, concentrations in supernatants of mesenteric lymph node cells (mesLNCs) isolated from naïve mice and cultured in vitro for 72 h in the presence of different doses of M. vaccae NCTC 11659 (100, 200, and 400 μg/mL) compared with respective PBS conditions.