IL10 and inflammatory bowel disease: A wide range of IBD-specific animal models were analyzed from the articles chosen for our review, such as the chemical colitogens 1-fluoro-2,4-dinitrobenzene (DNFB), dextran sulphate sodium (DSS), idoacetamide (IA), and 2,4,6-trinitrobenzene sulphonic (TNBS) acid, as well as biological models including the adoptive T-cell transfer in genetically modified mice that were interleukin-10 (IL-10)-deficient and were homozygous T-bet−/− Rag2−/− (also known as TRUC).