TIGIT and acute myeloid leukemia: Moreover, the highest frequencies of TIGIT+PVRIG+ cells were observed within the CD56dimCD16+ subpopulation (PB AML vs. PB HD p = 0.0019, BM AML vs. PB HD p = 0.0005; Figure 4C), whereas TIGIT+CD39+ cells were found mainly in the CD56brightCD16− NK cell population in AML (PB AML vs. PB HD p = 0.0003, BM AML vs. PB HD p < 0.0001; Figure 4C).