Following Dox induction (72 h), we observed that Zeb1 protein (Figure 1A,B) and RNA (Supplementary Figure S1A) expression were significantly decreased compared to all ctrl cells (p ≤ 0.05), down to a level equivalent to that of human LNCaP cells, an epithelial prostate cancer cell line. This evidence concerns the gene ZEB1 and Familial prostate cancer.