AKT1 and fibrosarcoma: Activated ERBB mediates various signaling pathways including the RAS (rat sarcoma)/RAF (rapidly accelerated fibrosarcoma), phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/AKT (a serine/threonine protein kinase), phospholipase C (PLC)-γ1, and signal transducer and activator of transcription (STAT) pathways [3].