Among these studies are investigations on blood glucose and insulin in obese non-diabetic individuals [42], on fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes [43] and on oxidative stress, glycemic control and renal function in pediatric patients with diabetic nephropathy [44]. The gene discussed is TNF; the disease is type 2 diabetes mellitus.