Given previous studies demonstrating the neuroprotective and mobility effects of PGZ at 1 μM in a Drosophila model of amyotrophic lateral sclerosis [37], we also analyzed the effects of 1 μM PGZ treatment on locomotor activity in the GBAΔTT/ΔTT mutant flies compared to the control GBA1+/+ flies. The gene discussed is GBA1; the disease is amyotrophic lateral sclerosis.