Hypoglycemia can be due to the inhibition of different pathways: of mitochondrial β-oxidation via the inhibition of CPT-I by malonyl-coA, of pyruvate carboxylase secondary to dicarboxylic aciduria, and of the tricarboxylic acid cycle via the inhibition of succinic acid dehydrogenase by malonic acid. This evidence concerns the gene PC and Hypoglycemia.