To establish independent predictors and adjusted odds ratios (aOR) for diagnosis of HRS-AKI, we conducted a multivariate analysis which showed that only a history of ascites, baseline serum creatinine >2.5 mg/dL on admission, albumin <2 g/dL, bilirubin >2 mg/dL and spontaneous bacterial peritonitis were statistically significant predictors for development of HRS (Table 3). This evidence concerns the gene ALB and Ascites.