GPT and hepatitis A virus infection: The scatter plots between ALT and HBsAg, HBeAg and HBV DNA of this study showed that the proportions of ALT ≥ 40 IU/L in patients with high levels of HBsAg, HBeAg and HBV DNA were all greater than 70%, which suggested that biochemically significant hepatitis activity was common in patients with high HBV replication.