In order to investigate if Venetoclax- or Venetoclax + Nilotinib-mediated cytotoxicity was dependent on apoptosis induction, we exposed CP-CML CD34-positive progenitors to Nilotinib, Venetoclax or their combination for 24 h and then we stained them by Annexin V and 7AAD (Figure 2A–D). The gene discussed is ANXA5; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.