ACE and myocardial infarction: Furthermore, before the index admission, patients with prior MI were more frequently receiving guidelines-directed medical therapy including aspirin (80.6% vs. 32.7%, p < 0.001), ACE-inhibitors/ARB’S (65% vs. 33.5% p < 0.001), beta blockers (55.3% vs. 20.7%, p < 0.001), and statins (61.9% vs. 28.6%, p < 0.001) (Supplementary Materials Table S1).