Subsequent work using a high throughput qMSP-based targeted approach, the investigators from the University of Groningen examined a targeted panel of 213 cancer-specific genes and derived a 4-gene panel (JAM3, EPB41L3 and TERT and C13ORF18) that was able to discriminate CIN3 and CC more accurately than conventional cytology [40]. This evidence concerns the gene TERT and cancer.