A significantly higher level of Hsp70 expression was found in human EAC (2.67 ± 0.21 A.U.)as compared to LGD (1.38 ± 0.18 A.U.)and most importantly non-dysplastic BE (0.22 ± 0.15 A.U., Fig. 1, A, C). This evidence concerns the gene HSPA1A and Barrett esophagus.