Wu et al. found that the expression of the anti-inflammatory cytokines IL-4, IL-10, and transforming growth factor (TGF)-β1 and TGF-β2 were upregulated in FAdV-4-infected chickens (19) and the infection of FAdV-4 could induce strong innate immune responses in chickens (20). This evidence concerns the gene TGFB2 and infection.