Moreover, the uni- and multivariate analyses suggested that TRIM46 expression (p = 0.002; HR = 1.836), age (p = 0.003; HR = 1.030), and histologic grade (p = 0.035; HR = 1.434) were independent biomarkers for overall survival (OS) of ccRCC (Figures 3A,B). This evidence concerns the gene TRIM46 and nonpapillary renal cell carcinoma.