The ORF-containing circRNAs produced by COL6A3 encodes a novel 198-aa functional peptide, and hsa_circ_0006401–198-aa promotes the stability of the host gene COL6A3 mrna, thereby facilitating CRC proliferation and translocation (Zhang et al., 2021c). This evidence concerns the gene COL6A3 and colorectal carcinoma.