PTEN and colorectal carcinoma: Circ-PTEN can promote CRC proliferation and translocation by acting as a miR-155 Circ-PTEN can increase the expression of its host gene PTEN by acting as a sponge for miR-155 and miR-330-3p, which in turn regulates the PI3K/AKT signaling pathway (Wang et al., 2021i).