AKT3 and glioblastoma: Xia et al., Found that circ-AKT3 encodes a novel 174 aa protein, AKT3-174aa, and overexpression of AKT3-174aa significantly reduced cell proliferation, radioresistance and tumorigenicity of GBM cells in vivo, while overexpression of circ-AKT3 suppressed the malignant phenotype of GBM(Xia et al., 2019).