MTOR and idiopathic membranous glomerulonephritis: Rapamycin, the selective inhibitor of mTOR protein kinase, was proved to reduce podocyte apoptosis by inhibiting the mTOR/P70S6K/4EBP1 signaling pathway and activating podocyte autophagy in idiopathic membranous nephropathy (IMN) mice model (Wu et al., 2013).