On the contrary, the demethylation of GSTP1 via DNA methyltransferase inhibitor 5-Aza-CdR could weaken 5-FU resistance in LINC01419 overexpressed ESCC cells, demonstrating that LINC01419 functions as a modulator of 5-FU-based chemotherapy sensitivity in ESCC (Chen J. L. et al., 2019). The gene discussed is GSTP1; the disease is esophageal squamous cell carcinoma.