Via the miR-195/Akt/mTOR axis, ectopic expression of FOXD2-AS1, an up-regulated lncRNA in ESCC patients and DDP resistant ESCC cells (TE-1/DDP), could contribute to DDP resistance in ESCC (Liu H. et al., 2020). This evidence concerns the gene FOXD2 and esophageal squamous cell carcinoma.