Ectopic miR-544 and miR-338-5p could overcome DDP resistance of esophageal cancer via targeting and down-regulating oncogene E2F transcription factor 5 (E2F5) and fermitin family homolog 2 (FERMT2) (Lin W. C. et al., 2019; Sun et al., 2019). Here, E2F5 is linked to esophageal cancer.