GPC3 and cancer: For instance, increased expression of CD69, BTG2, MMP14, PCDH7, GPC3, and NMUR1 was linked to greater drug sensitivity of cancer cells to drugs such as oxaliplatin, vemurafenib, trametinib, paclitaxel, vinblastine, etc. The MRP family consists of 13 members, with MRP1–MRP9 being the primary transporters implicated in multidrug resistance via extruding anticancer medicines from tumor cells (Sodani et al., 2012).