Tumor-related signal pathways like MAPK, p53, and JAK-STAT were considerably enriched in the GSEA analysis, and incessant activation of these pathways is connected to LUAD, which could be new treatment targets (Chou et al., 2019; Mohrherr et al., 2019; Stutvoet et al., 2019). The gene discussed is TP53; the disease is neoplasm.