In a Foxo1/3 dKO murine model for adult GCT, SOX9 was not present in normal granulosa cells; however, it was present in the nuclei of some granulosa cells with follicle-like structures that were apparently missing from the oocytes, as well as in the nuclei of many tumor granulosa cells located within tubular structures. This evidence concerns the gene SOX9 and neoplasm.