Results showed that PDGFR-α and MBP were increased in OPC group compared with NS vehicle control and reduced in the AMD3100 co-administration group (Fig. 3B; PDGFR-α, p (NS vs OPC) = 0.001, p (OPC vs OPC+AMD) = 0.010; MBP, p (NS vs OPC) = 0.030, p (OPC vs OPC+AMD) = 0.048). Here, PDGFRA is linked to age-related macular degeneration.