Overexpression of lncRNA ZFPM2-AS1 in HCC tissue was correlated with poorer overall survival, and through in vitro functional analysis, ZFPM2-AS1 was found to act as miRNA sponge for promoting HCC cell proliferation, apoptosis, migration, and invasion via multiple axes (He et al., 2020; Liu et al., 2020; Zhang et al., 2021). This evidence concerns the gene ZFPM2 and hepatocellular carcinoma.