KLF12 and cancer: KLF12 is a significant quantitative trait locus from multiple GWAS (Genome-Wide Association Studies) for a host of non-pregnancy associated outcomes such as cancers (Petersen et al., 2010), lipids (Kathiresan et al., 2007), eye disorders (Macgregor et al., 2010), sudden cardiac arrest (Aouizerat et al., 2011), and heart function abnormalities (Sotoodehnia et al., 2010).