KLF1 and Congenital hemolytic anemia: Two dominant monoallelic mutations in mammalian EKLF are causative for hematologic deficiencies: the mouse Nan mutation (E339D) leads to hemolytic neonatal anemia, and the human CDA mutation (E325K) causes congenital dyserythropoietic anemia (CDA) type IV (reviewed in Kulczynska-Figurny et al. (2020)).