ISM1 and diabetes mellitus: As expected, many genes merely changed in the sDM group, such as SULF2, GFAP (Pang et al., 2017), ABCG1 (Daffu et al., 2015), GCK (Haeusler et al., 2015), ISM1 (Liu et al., 2019), and CORIN (Pang et al., 2015) (Figure 3E), have been associated with diabetes.