These included the integrin1 pathway, VEGFA targets, tumor tumorigenesis, JNK signaling dn, metastasis epithelial-mesenchymal transition (EMT) up, PI3K cascade: FGFR2, metastasis, Wnt signaling pathway, TGF beta signaling pathway, tumor vasculature up, calcium signaling pathway, cell substrate adhesion, G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger, vascular endothelial growth factor signaling pathway, positive regulation of Erk1 and Erk2 cascade and adherens junction assembly (Fig. 10A–P, Table S2). This evidence concerns the gene MAPK8 and neoplasm.