Tumor immune infiltration abundance of macrophage also shown a significantly associated with CDH2 (r = 0.474, P = 3.59 × 10−22), CDH6 (r = 0.418, P = 4.20 × 10−17) and CDH10 (r = 0.492, P = 6.60 × 10−24) in GC tumor tissues. The gene discussed is CDH2; the disease is neoplasm.