We extended the analysis of available RNA-seq datasets to data from cultured human control and FSHD derived myoblasts and myotubes (Supplementary Figure 8)37, skeletal muscle biopsies from control and FSHD individuals (Supplementary Figure 9)37 and control myocytes during differentiation (Supplementary Figure 10)38 as DUX4 expression is dynamically regulated during muscle cell differentiation36. This evidence concerns the gene DUX4 and Facioscapulohumeral dystrophy.