HLA-DRB1 and asthma: Finally, transcriptomic data from bronchial brushing and bronchoalveolar lavage (BAL) samples revealed that HLA-DQA1 (only available for bronchial brushing), HLA-DQB1, and HLA-DRB1 were downregulated in patients with severe asthma compared to healthy controls (Supplementary Figure S3 and Supplementary Figure S4).