Since CD8+ T cells also have complementary roles in asthma and autoimmune conditions29–31 and both murine and human CD4+ and CD8+ T cells both exhibit increased decorin expression in the setting of asthma, future studies will be required to define the individual contributions of each T cell population to the suppression of microglia-mediated optic gliomagenesis. This evidence concerns the gene CD4 and asthma.