After combining clinical traits, we found that IDH-wildtype GBM positively correlated with turquoise (R = 0.63, p = 3e−37) and yellow (R = 0.37, p = 1e−11) modules, but negatively correlated with blue (R = −0.52, p = 1e−23) and brown (R = −0.38, p = 1e−12) modules (Fig. 1A). This evidence concerns the gene IDH1 and glioblastoma.