TP53 and ovarian cancer: However, based on the GEO datasets of ovarian cancer, high expression of FASN was found to be related to poor OS in the stage/ stage 2/3/4 subgroup, PFS in the histology/serous or TP53/mutated subgroups, and PPS in the histology/serous, debulk/optimal, and chemotherapy/ containing platin subgroups (Supplementary Table 3).