Figure 10B shows the types, sites, and number of FASN genetic alterations. The missense mutation of FASN is the principal type of genetic alteration. L1353Sfs*20 alteration (four cases of uterine endometrioid carcinoma and one case of stomach adenocarcinoma) between Methyltransf_12 and ADH_zinc_N could induce a translation mutation from L (leucine) to S (serine) at the 1353 site of the FASN protein (Figure 10B). The L1353 locus was identified in the 3D protein structure (Figure 10C). This evidence concerns the gene FASN and endometrial endometrioid adenocarcinoma.