CD40 and asthma: Significant relationships (FDR < 0.05), in addition to those of the main analysis, were found for some of the stricter settings (Table 3), such as a protective effect of CD40 on psoriasis (OR = 0.92, 95% CI = 0.88 to 0.96) and harmful effects of IL-18R1 on asthma (OR = 1.02, 95% CI = 1.01 to 1.02 and OR = 1.02, 95% CI = 1.01 to 1.03) and on celiac disease (OR = 1.06, 95% CI = 1.02 to 1.09).