Murakami, et al.22 (2000) reported lower SCCA1 at mRNA level in cervical SCC than in the normal cervical tissue.Barnes, Coulter and Worrall23 (2000) found a lower SCCA1 production in cases with cervical squamous cell cancer than in those with a healthy cervix. This evidence concerns the gene SERPINB4 and cervical squamous cell carcinoma.