Thus, the combined decreased expression of Kcna3 (Kv1.3), Kcnk9 (TASK3), Kcnn3 (SK3), Kcng3 (Kv7.3), and Kcns3 (Kv9.3) around day 8 could lead to increased chances of persistent membrane depolarization, which ultimately may lead to epilepsy. The gene discussed is KCNN3; the disease is epilepsy.