As shown in Figure 2D, the protein expression levels of phosphorylated STAT3 (pSTAT3) and its downstream target MYC in the senescence-like CAF CM group were upregulated compared with those in the CAF CM group, whereas the control group (NSCLC cells cultured with normal medium) had the lowest protein expression levels. The gene discussed is STAT3; the disease is non-small cell lung carcinoma.