Recent studies have also indicated that anti-O-specific polysaccharide antibodies in sera from humans surviving cholera can agglutinate Vibrio and prevent motility (Charles et al., 2020), and that expression of a monoclonal human anti-LPS IgA1 in mice can provide passive protection to infants from milk (Baranova et al., 2020). Here, IGHA1 is linked to vibrio infectious disease.