Current research used combinatory immunocytochemistry/laser-catapult microdissection/Western blot technology to procure pure GABA nerve cell samples from the VMNvl to address the premise that these cells exhibit correlated changes in GAD and pAMPK protein expression in reaction to acute hypoglycemia, and moreover, that these responses are each attenuated during RIIH. The gene discussed is GAD1; the disease is Hypoglycemia.