In addition, abnormal EC between the fusiform gyrus and the frontal gyrus, the occipital lobe was identified and associated with diabetes-related characteristics (e.g., insulin and plasma glucose levels) in T2DM patients, while the abnormal EC between SFG and several regions including the frontal and motor areas was correlated with disease duration and cognitive function. The gene discussed is INS; the disease is type 2 diabetes mellitus.