ANGPTL4 is a malfunctioned protein and potential treatment target in various diseases and has been found to be involved in several nonmetabolic and metabolic conditions, both physiological and pathological, including vascular permeability and angiogenesis, cell differentiation, lipid metabolism, tumor genesis, energy homeostasis, glucose homoeostasis, redox regulation, wound healing, and inflammation [29]. The gene discussed is ANGPTL4; the disease is neoplasm.