Furthermore, apoptotic cell death induced by BIX was completely inhibited by treatment with benzyloxycarbonyl-Val-Ala-Asp-(OMe) fluoromethyl ketone (zVAD-fmk; Fig. 1c, d), indicating that BIX induces apoptotic cell death in EGFR-mutant NSCLC cells in a caspase-dependent manner. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.