AVPR1A and Anxiety: Since the modulation of DA and vasopressin receptors has been found to affect cognition, anxiety, and neuronal survival, we evaluated the binding affinity of ILG to the D1R, D2R, D3R, D4R, and V1AR receptors to determine whether ILG can target these receptors and identified significant binding to D1R, D3R, and V1AR. The functional GPCR assay showed ILG to have D1R antagonist and D3R and V1AR agonist properties.