ANGPT2 and hydrops fetalis: Two of the authors recently reported heterozygous pathogenic sequence variants in ANGPT2 as a cause of dominantly inherited primary lymphoedema.24 Here, we report a homozygous variant, NM_001147.2:c.557A>G r.557_566del, in a consanguineous family with recurrent, severe, early-onset hydrops fetalis.