Damage-associated molecular patterns (DAMPs) such as S100A8/9, high mobility group box 1 (HMGB1), or uric acid are released from damaged cells under a variety of pathological conditions including cancer and have been implicated in leukocyte trafficking.19 Consequently, these DAMPs might mediate the recruitment of excessively aging neutrophils in cancer to malignant tumors. Here, S100A8 is linked to cancer.