Among the genes within the network, IL (degrees of freedom = 4), BCL2L1 (degrees of freedom = 3), BCL2 (degrees of freedom = 3), TNF (degrees of freedom = 3), CASP9 (degrees of freedom = 3), PIK3CA (degrees of freedom = 3), CASP3 (degrees of freedom = 3), and NGF (degrees of freedom = 3) were found to have the most connections with various compounds in HE, suggesting they are potential targets of HE. The gene discussed is CASP3; the disease is hereditary elliptocytosis.