IDH1 and central nervous system cancer: In recent years, great progress has been made in the molecular pathology of nervous system malignant tumours, and a series of molecular markers, such as MGMT promoter methylation, IDH mutations, chromosome 1p/19q co-deletion and TERT promoter mutations, have been found that are helpful for the clinical diagnosis and prediction of the formation, invasion, progression and prognosis of glioma [7, 8].